BDBM50429366 CHEMBL2336316

SMILES COc1cc(ccc1OCCCNC(=O)Nc1ccc(cc1)C(F)(F)F)-c1nc2ccc(Cl)cn2c1NC(C)C

InChI Key InChIKey=MDYFKHRXLNMCBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50429366   

TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50429366(CHEMBL2336316)
Affinity DataIC50: 104nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50429366(CHEMBL2336316)
Affinity DataIC50: 439nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed