BDBM50429924 CHEMBL2333414

SMILES NNc1c(F)c(F)c(c(F)c1F)S(N)(=O)=O

InChI Key InChIKey=LXAQZCRVFSTIKS-UHFFFAOYSA-N

Data  1 KI  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50429924   

TargetCarbonic anhydrase 1(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429924(CHEMBL2333414)
Affinity DataKd:  8.30nMpH: 7.0Assay Description:Binding affinity to human recombinant CA1 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429924(CHEMBL2333414)
Affinity DataKd:  91nMpH: 7.0Assay Description:Binding affinity to human recombinant CA2 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429924(CHEMBL2333414)
Affinity DataKd:  140nMpH: 7.0Assay Description:Binding affinity to human recombinant CA13 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429924(CHEMBL2333414)
Affinity DataKd:  465nMpH: 7.0Assay Description:Binding affinity to human recombinant CA7 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429924(CHEMBL2333414)
Affinity DataKi:  465nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429924(CHEMBL2333414)
Affinity DataKd:  769nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed