BDBM50430606 CHEMBL2338714::Isopentyl Orvinol M320

SMILES CO[C@]12C=C[C@@]3(C[C@@H]1[C@](C)(O)CCC(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45

InChI Key InChIKey=MFIWLPVODKSMKX-XELDOGJXSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50430606   

TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50430606(CHEMBL2338714 | Isopentyl Orvinol M320)
Affinity DataKi:  0.0820nMAssay Description:Displacement of [3H]-diprenorphine from human KOR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rat)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50430606(CHEMBL2338714 | Isopentyl Orvinol M320)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]-diprenorphine from rat recombinant MOR expressed in rat C6 cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rat)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50430606(CHEMBL2338714 | Isopentyl Orvinol M320)
Affinity DataEC50:  1nMAssay Description:Agonist activity at rat recombinant MOR expressed in rat C6 cells assessed as stimulation of [35S]GTPgammaS binding after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50430606(CHEMBL2338714 | Isopentyl Orvinol M320)
Affinity DataEC50:  0.0510nMAssay Description:Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed