BDBM50431028 CHEMBL2338333
SMILES CN1C\C(=C/c2ccccn2)C(=O)\C(C1)=C\c1ccccn1
InChI Key InChIKey=VCLPNFMJSSBBKX-WFYKWJGLSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50431028
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of recombinant MAPKAPK2 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant MAPK14 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant NEK1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of recombinant ERK2 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant AKT1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of recombinant RAF1 (unknown origin) by cascade reaction assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Human)
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant RPS6K1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant IKBKB (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant AKT2 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant MEK1 (unknown origin) by cascade reaction assayMore data for this Ligand-Target Pair