BDBM50431081 CHEMBL2338805::US10202399, Example 23

SMILES COc1cc(CCc2cc(O)c(=O)[nH]n2)cc(OC)c1

InChI Key InChIKey=ZDHDWGYWUPEHEN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50431081   

TargetD-amino-acid oxidase(Mouse)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431081(CHEMBL2338805 | US10202399, Example 23)
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431081(CHEMBL2338805 | US10202399, Example 23)
Affinity DataIC50: 13nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431081(CHEMBL2338805 | US10202399, Example 23)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431081(CHEMBL2338805 | US10202399, Example 23)
Affinity DataIC50: 19nMAssay Description:Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431081(CHEMBL2338805 | US10202399, Example 23)
Affinity DataIC50: 25nMAssay Description:Inhibition of human full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed