BDBM50431131 CHEMBL2332056

SMILES O=C(Nc1ccc(-c2cn[nH]c2)cc1)NC(CCO)c1cccc(F)c1

InChI Key InChIKey=BNSKTIACOBJLNV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50431131   

TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431131BDBM50431131(CHEMBL2332056)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431131BDBM50431131(CHEMBL2332056)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin) after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431131BDBM50431131(CHEMBL2332056)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF modeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431131BDBM50431131(CHEMBL2332056)
Affinity DataIC50: 10nMAssay Description:Inhibition of ROCK1 (unknown origin) after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431131BDBM50431131(CHEMBL2332056)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin) using LCD-AKRRRRLSSLRA-NH2 as substrate after 75 mins by luminescence assay in presence of [33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431131BDBM50431131(CHEMBL2332056)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of JNK3 alpha1 (unknown origin) using biotinylated Flag-ATF2 as substrate after 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed