BDBM50431213 CHEMBL2332604

SMILES [#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6@@H]-2-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6@@H]-2-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6@@H]-2-[#6]-[#16]-[#6]-c3cc(-[#6]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c4ccc(-[#8])cc4)-[#7]-[#6]-1=O)-[#6](=O)-[#7]-[#6]-[#6](-[#8])=O)cc(-[#6]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-2)c3

InChI Key InChIKey=NPDDURCZQPXQII-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50431213   

TargetPlasma kallikrein(Human)
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant polyhistidine-tagged plasma kallikrein expressed in Escherichia coli XL1 blue using Z-FR-AMC as substrate by fluorime...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human tPA using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human uPA using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human trypsin using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human coagulation factor 11a using Boc-Phe-Ser-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human PK using Z-Phe-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProthrombin(Human)
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human thrombin using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPlasminogen(Human)
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed