BDBM50431843 CHEMBL2347241::US10112895, Compound 3

SMILES NS(=O)(=O)c1ccc(NCc2cc(Cl)ccc2OCc2ccccc2)cc1

InChI Key InChIKey=NLAZPVBNHPQLFJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50431843   

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

US Patent
LigandPNGBDBM50431843(CHEMBL2347241 | US10112895, Compound 3)
Affinity DataEC50:  1.39E+4nMpH: 7.5Assay Description:Processive DNA synthesis was assessed by two types of assays: the Rapid Plate Assay and the M13 assay. The Rapid Plate Assay was performed as previou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

TargetSignal transducer and activator of transcription 3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50431843(CHEMBL2347241 | US10112895, Compound 3)
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of IL-6-induced STAT3 pathway in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed