BDBM50432892 CHEMBL2376650

SMILES C[C@@H](Oc1c[nH]c(=O)c(c1)C(=O)Nc1ccc(cc1)N1CCN(C)CC1)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=CEYWYXBKNMNKBH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50432892   

TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50432892(CHEMBL2376650)
Affinity DataIC50: 12nMAssay Description:Inhibition of c-MET (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50432892(CHEMBL2376650)
Affinity DataIC50: 281nMAssay Description:Inhibition of ABL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50432892(CHEMBL2376650)
Affinity DataIC50: 446nMAssay Description:Inhibition of RON (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50432892(CHEMBL2376650)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TYRO3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50432892(CHEMBL2376650)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50432892(CHEMBL2376650)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed