BDBM50432894 CHEMBL2376648::US9126947, 1

SMILES C[C@@H](Oc1cc(nnc1N)C(=O)Nc1ccc(cc1)C(=O)N1CCN(C)CC1)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=ONPGOSVDVDPBCY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50432894   

TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50432894(CHEMBL2376648 | US9126947, 1)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50432894(CHEMBL2376648 | US9126947, 1)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Xcovery Holding

US Patent
LigandPNGBDBM50432894(CHEMBL2376648 | US9126947, 1)
Affinity DataIC50: 1nMT: 2°CAssay Description:Assays were performed as described in Fabian et al. (2005) Nature Biotechnology, vol. 23, p. 329 and in Karaman et al. (2008) Nature Biotechnology, v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
US Patent