BDBM50434121 CHEMBL2381492

SMILES c1cc2c(cc1Br)NC(=O)C2

InChI Key InChIKey=JARRYVQFBQVOBE-UHFFFAOYSA-N

Data  2 IC50  2 EC50

PDB links: 6 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50434121   

TargetAryl hydrocarbon receptor(Human)
Palacky University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434121BDBM50434121(CHEMBL2381492)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
Palacky University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434121BDBM50434121(CHEMBL2381492)
Affinity DataEC50:  1.86E+4nMAssay Description:Inhibition of human c-Met in human GTL16 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Palacky University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434121BDBM50434121(CHEMBL2381492)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434121BDBM50434121(CHEMBL2381492)
Affinity DataIC50: 5.70E+5nMAssay Description:Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)