BDBM50434287 CHEMBL2386346
SMILES CCOc1cc(ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@](C)(N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1)c1ccc(Cl)cc1)C(C)(C)C
InChI Key InChIKey=QBGKPEROWUKSBK-QPPIDDCLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50434287
Affinity DataIC50: 18nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.90nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of MDM2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to recombinant human GST-tagged HDM2More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair