BDBM50434289 CHEMBL2386344

SMILES CCOc1cc(ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@](C)(N1C(=O)N1CCN(CCC(F)(F)F)CC1)c1ccc(Cl)cc1)C(C)(C)C

InChI Key InChIKey=MVGHTOGJZPPSRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434289   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50434289(CHEMBL2386344)
Affinity DataIC50: 22nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed