BDBM50434749 CHEMBL2385586
SMILES C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1cn[nH]c1
InChI Key InChIKey=WMTXIPYJYDISKM-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50434749
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 129nMAssay Description:Inhibition of ALK6 (unknown origin)More data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
TargetActivin receptor type-1B(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of ALK4 (unknown origin)More data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 3.32E+3nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair