BDBM50434804 CHEMBL2386650

SMILES C[C@@H](O)c1nc2cnc3[nH]ccc3c2n1[C@@H]1CCCN(C1)C(=O)CC(F)(F)F

InChI Key InChIKey=SMHDJPTUYOMJEU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434804   

TargetTyrosine-protein kinase JAK1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50434804(CHEMBL2386650)
Affinity DataKi:  43nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using Val-Ala-Leu-Val-Asp-Gly-Tyr-Phe-Arg-Leu-Thr-Thr as substrate after 30 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed