BDBM50435004 CHEMBL2386284

SMILES CC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN)cc1)c1ccccc1

InChI Key InChIKey=YCQBLTPGQSYLHD-UHFFFAOYSA-N

Data  2 KI  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50435004   

TargetEstrogen receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50435004(CHEMBL2386284)
Affinity DataEC50:  17nMAssay Description:Displacement of fluorescent ES2 from recombinant human ERalpha after 2 hrs in absence of light by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50435004(CHEMBL2386284)
Affinity DataEC50:  28nMAssay Description:Displacement of fluorescent ES2 from recombinant human ERbeta after 2 hrs in absence of light by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetAromatase(Human)
State University of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50435004(CHEMBL2386284)
Affinity DataIC50: 30nMAssay Description:Inhibition of human placental microsomal aromatase using testosterone as substrate assessed as formation of estradiol after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetAromatase(Human)
State University of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50435004(CHEMBL2386284)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant placental aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAromatase(Human)
State University of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50435004(CHEMBL2386284)
Affinity DataKi:  442nMAssay Description:Inhibition of human recombinant microsomal aromatase using 7-methoxy-4-trifluoromethylcoumarin as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAromatase(Human)
State University of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50435004(CHEMBL2386284)
Affinity DataKi:  442nMAssay Description:Inhibition of human recombinant microsomal aromatase using 7-methoxy-4-trifluoromethylcoumarin as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAromatase(Human)
State University of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50435004(CHEMBL2386284)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human recombinant microsomal aromatase-mediated 7-methoxy-4-trifluoromethylcoumarin conversion to 7-hydroxytrifluoromethylcoumarin prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAromatase(Human)
State University of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50435004(CHEMBL2386284)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human recombinant microsomal aromatase-mediated 7-methoxy-4-trifluoromethylcoumarin conversion to 7-hydroxytrifluoromethylcoumarin prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAromatase(Human)
State University of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50435004(CHEMBL2386284)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of recombinant human microsomal CYP19 using MFC as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed