BDBM50435667 CHEMBL2391796

SMILES O[C@H](COc1cc(O)ccc1C(=O)N1CC[C@@H](O)C1)CN1CCC2(Cc3cc(Cl)ccc3O2)CC1

InChI Key InChIKey=JDTCZRQCZFSKET-RTWAWAEBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435667   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50435667(CHEMBL2391796)
Affinity DataIC50:  7.90nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage inflammatory protein-1 alpha receptor(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50435667(CHEMBL2391796)
Affinity DataIC50:  1.40E+4nMAssay Description:Antagonist activity at rat CCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed