BDBM50435667 CHEMBL2391796
SMILES O[C@H](COc1cc(O)ccc1C(=O)N1CC[C@@H](O)C1)CN1CCC2(Cc3cc(Cl)ccc3O2)CC1
InChI Key InChIKey=JDTCZRQCZFSKET-RTWAWAEBSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50435667
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetMacrophage inflammatory protein-1 alpha receptor(Rattus norvegicus)
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Antagonist activity at rat CCR1More data for this Ligand-Target Pair