BDBM50435771 CHEMBL2393168

SMILES FC(F)(F)C1CCN(CCN1)S(=O)(=O)c1ccc(NC(=O)NCc2cccnc2)cc1

InChI Key InChIKey=ORDWPEHFKJXJKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435771   

TargetNicotinamide phosphoribosyltransferase(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50435771(CHEMBL2393168)
Affinity DataIC50: 3nMAssay Description:Inhibition of NAMPT (unknown origin) assessed as NAM conversion to NMN preincubated for 15 mins prior to substrate addition measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50435771(CHEMBL2393168)
Affinity DataIC50: 110nMAssay Description:Inhibition of CYP2C9 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed