BDBM50435784 CHEMBL2393190::US11279687, Compound 134
SMILES C[C@H]1CN(C[C@@H](C)O1)S(=O)(=O)c1ccc(NC(=O)NCc2cccnc2)cc1
InChI Key InChIKey=ZZZBYLFRFPPGEA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50435784
Affinity DataIC50: 3.90nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of NAMPT (unknown origin) assessed as NAM conversion to NMN preincubated for 15 mins prior to substrate addition measured after 30 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of CYP2C9 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair