BDBM50435876 CHEMBL2391074

SMILES Clc1ccc(cc1)S(=O)(=O)N1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=FDOUWHOQTJKHEX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435876   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Saud University

US Patent
LigandPNGBDBM50435876(CHEMBL2391074 | US12139461, Compound C29)
Affinity DataIC50: 250nMAssay Description:Phosphodiesterase type 5 (PDE5) inhibition assay of compounds of formula I, III, and IV and the reference drug sildenafil were performed according to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2025
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Nstri

Curated by ChEMBL
LigandPNGBDBM50435876(CHEMBL2391074 | US12139461, Compound C29)
Affinity DataKi:  551nMAssay Description:Displacement of [3H](+)pentazocine from sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 120 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed