BDBM50436984 CHEMBL2402458

SMILES C[C@]1(CCC[C@]2(C)[C@@H]1CC[C@@]13C[C@H](C[C@H](O)[C@@H]21)C(=C)[C@H]3O)NC(=O)Nc1ccc(F)cc1

InChI Key InChIKey=WZBMHZHKXSXVOJ-SZUYDZFMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50436984   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50436984(CHEMBL2402458)
Affinity DataIC50:  249nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cell microsomes assessed as inhibition of [3H]cortisone conversion to [3H]cortisol by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50436984(CHEMBL2402458)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50436984(CHEMBL2402458)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cell microsomes assessed as inhibition of [3H]cortisone conversion to [3H]cortisol by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed