BDBM50437202 CHEMBL478480

SMILES Brc1ccccc1\C=C1/CCC\C(=C/c2ccccc2Br)C1=O

InChI Key InChIKey=IYUMKWYJTLIPIV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50437202   

Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50437202(CHEMBL478480)
Affinity DataIC50: 148nMAssay Description:Inhibition of 11beta-HSD1 in Sprague-Dawley rat leydig cells at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50437202(CHEMBL478480)
Affinity DataIC50: 218nMAssay Description:Inhibition of 11beta-HSD1 in rat testis microsomes using [3H]-11-DHC as substrate assessed as formation of CORT after 60 to 90 mins by radiometric an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50437202(CHEMBL478480)
Affinity DataIC50: 346nMAssay Description:Inhibition of human 11beta-HSD1 transfected in CHOP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50437202(CHEMBL478480)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]-cortisone as substrate assessed as formation of cortisol after 60 to 90 mins by radiom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed