BDBM50437850 CHEMBL2407747

SMILES CCc1ccc2NC(=O)\C(=C\c3ccc4c(\C=C\c5cccnc5)n[nH]c4c3)c2c1

InChI Key InChIKey=OLRQMHGOBAYXHZ-FPQBULDBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50437850   

TargetSerine/threonine-protein kinase PLK3(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50437850(CHEMBL2407747)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLK3 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PLK4(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50437850(CHEMBL2407747)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of N-terminal GST-tagged human PLK4 (1 to 391 amino acids) expressed in Escherichia coli using TMB as substrate after 30 mins by indirect ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PLK1(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50437850(CHEMBL2407747)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PLK2(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50437850(CHEMBL2407747)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLK2 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed