BDBM50437858 CHEMBL2407910

SMILES O=C1Nc2ccccc2\C1=C\c1ccc2[nH]ncc2c1

InChI Key InChIKey=HKGXDXUDOHQKPM-JYRVWZFOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50437858   

TargetSerine/threonine-protein kinase PLK3(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50437858(CHEMBL2407910)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of PLK3 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PLK4(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50437858(CHEMBL2407910)
Affinity DataIC50:  390nMAssay Description:Inhibition of N-terminal GST-tagged human PLK4 (1 to 391 amino acids) expressed in Escherichia coli using TMB as substrate after 30 mins by indirect ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PLK1(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50437858(CHEMBL2407910)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PLK2(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50437858(CHEMBL2407910)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of PLK2 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed