BDBM50437860 CHEMBL2407912

SMILES Fc1ccc2NC(=O)\C(=C\c3ccc4cn[nH]c4c3)c2c1

InChI Key InChIKey=HOOFEYTZWSBHNO-WLRTZDKTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50437860   

TargetSerine/threonine-protein kinase PLK2(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50437860(CHEMBL2407912)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of PLK2 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PLK4(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50437860(CHEMBL2407912)
Affinity DataIC50:  60nMAssay Description:Inhibition of N-terminal GST-tagged human PLK4 (1 to 391 amino acids) expressed in Escherichia coli using TMB as substrate after 30 mins by indirect ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PLK1(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50437860(CHEMBL2407912)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of PLK1 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed