BDBM50438849 CHEMBL2420479
SMILES O=c1nc2n(-c3cccc4[nH]ncc34)c3cc(ccc3cc2c(=O)[nH]1)C#N
InChI Key InChIKey=KDFUHGSKLVUMTH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50438849
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of APE-1 (unknown origin) using double-stranded AP-site containing DNA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataEC50: 370nMAssay Description:Inhibition of TDP2 (unknown origin) using 4-nitrophenyl phenylphosphonate as substrate after 60 minsMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of TDP2 (unknown origin) using 5'-Y-TCCGTTGAAGCCTGCTTT-3' as substrate after 60 minsMore data for this Ligand-Target Pair