BDBM50439299 CHEMBL2419521::US10696692, Example 268

SMILES O=C(NCc1ccc(cc1)S(=O)(=O)C1CCCOC1)N1Cc2ccncc2C1

InChI Key InChIKey=YADXVYOBJXXUFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439299   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM50439299(CHEMBL2419521 | US10696692, Example 268)
Affinity DataIC50: 17.3nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM50439299(CHEMBL2419521 | US10696692, Example 268)
Affinity DataIC50: 44nMAssay Description:Inhibition of human NAMPT using NAM/PRPP as substrate incubated for 15 mins prior to substrate addition measured after 30 mins by mass spectrometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed