BDBM50439309 CHEMBL2419513

SMILES FC(F)(F)c1cncc(c1)S(=O)(=O)c1ccc(CNC(=O)N2Cc3ccncc3C2)cc1

InChI Key InChIKey=QGGGMKABEQLQRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439309   

TargetNicotinamide phosphoribosyltransferase(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50439309(CHEMBL2419513)
Affinity DataIC50: 15nMAssay Description:Inhibition of human NAMPT using NAM/PRPP as substrate incubated for 15 mins prior to substrate addition measured after 30 mins by mass spectrometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed