BDBM50439432 CHEMBL2420703

SMILES Cn1cc(c(n1)-c1ccc(F)cc1)-c1ccnc2CNCCOc12

InChI Key InChIKey=RDUXJEGWTNOYDA-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439432   

TargetCasein kinase I isoform delta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439432(CHEMBL2420703)
Affinity DataIC50:  42nMAssay Description:Inhibition of human CK1 delta transfected in african green monkey cos7 cells after overnight incubation by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCasein kinase I isoform delta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439432(CHEMBL2420703)
Affinity DataIC50:  6nMAssay Description:Inhibition of CK1 delta (unknown origin) using PLSRTLpSVASLPGL as substrate after 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCasein kinase I isoform epsilon(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439432(CHEMBL2420703)
Affinity DataIC50:  27nMAssay Description:Inhibition of CK1 epsilon (unknown origin) using PLSRTLpSVASLPGL as substrate after 85 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)