BDBM50440317 CHEMBL2424898

SMILES COc1ccc2nccc(NC(=O)[C@@H]3CC[C@H](CO3)NCc3cc4OCCOc4cn3)c2n1

InChI Key InChIKey=HDUOQGPJPLEPTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440317   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440317(CHEMBL2424898)
Affinity DataIC50: 125nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440317(CHEMBL2424898)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of wild type Staphylococcus aureus ATCC 29213 topoisomerase-4 subunit 2GrlA/2GrlB assessed as pBR322 relaxation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed