BDBM50440441 CHEMBL2425846

SMILES Nc1c2CCCCc2nc2Oc3c(C(c4ccc(F)cc4)c12)c(=O)oc1ccccc31

InChI Key InChIKey=DHAXWBWQDZCBTC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50440441   

TargetAcetylcholinesterase(Electric eel)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50440441(CHEMBL2425846)
Affinity DataIC50: 5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50440441(CHEMBL2425846)
Affinity DataKi:  22nMAssay Description:Mixed-type inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50440441(CHEMBL2425846)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed