BDBM504406 US11040034, Ex. No. 84

SMILES Clc1ccc2nc(-c3cnnc(c3)C3CC3)n(C3CC3)c2n1

InChI Key InChIKey=VSWYJFLOCACQIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504406   

TargetCytochrome P450 11B2, mitochondrial(Human)
Phasebio Pharmaceuticals

US Patent
LigandPNGBDBM504406(US11040034, Ex. No. 84)
Affinity DataIC50: 50nMAssay Description:Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Phasebio Pharmaceuticals

US Patent
LigandPNGBDBM504406(US11040034, Ex. No. 84)
Affinity DataIC50: 550nMAssay Description:Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent