BDBM50440789 CHEMBL2431248

SMILES CN1C[C@](C)(N(CC(=O)Nc2ccc3C[C@]4(Cc3c2)C(=O)Nc2ncccc42)C(=O)C11CCCC1)c1cc(F)cc(F)c1

InChI Key InChIKey=WYWHBLFVASSGIJ-AJQTZOPKSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50440789   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440789(CHEMBL2431248)
Affinity DataKi:  0.0460nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440789(CHEMBL2431248)
Affinity DataIC50:  0.0970nMAssay Description:Antagonist activity at CGRP receptor (unknown origin) by cell based cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Labortories

Curated by ChEMBL
LigandPNGBDBM50440789(CHEMBL2431248)
Affinity DataIC50:  0.390nMAssay Description:Antagonist activity at CGRP receptor (unknown origin) by cell based cAMP assay in presence of human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed