BDBM50441103 CHEMBL2430577

SMILES CCCOc1c2Cc3cccc(Cc4cccc(Cc5cc(cc(Cc1ccc2)c5O)C(O)(P(O)(O)=O)P(O)(O)=O)c4OCCC)c3O

InChI Key InChIKey=WHSUUZXAOAGSJL-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50441103   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataKi:  680nMAssay Description:Reversible inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of recombinant truncated PTP1B (unknown origin) using pTyr1146 as substrate assessed as inorganic phosphate level after 20 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CD45 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of PTPbeta (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed