BDBM50441298 CHEMBL2431708

SMILES Oc1c(cccc1-c1cccc(c1)C(F)(F)P(O)(O)=O)C1CCCCC1

InChI Key InChIKey=JUSLBFDSFUTQKT-UHFFFAOYSA-N

Data  5 KI  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50441298   

TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50441298(CHEMBL2431708)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50441298(CHEMBL2431708)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibition of human TC-PTP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50441298(CHEMBL2431708)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein phosphatase C(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50441298(CHEMBL2431708)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human CD45 using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein phosphatase F(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50441298(CHEMBL2431708)
Affinity DataKi: >9.00E+5nMAssay Description:Inhibition of human LAR using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50441298(CHEMBL2431708)
Affinity DataKd:  7.04E+4nMAssay Description:Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)