BDBM50441342 CHEMBL2431765::US9394263, 29
SMILES CN[C@@H](C)C(=O)N[C@H]1COc2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O
InChI Key InChIKey=NYZLBAGNVDGXCG-YWZLYKJASA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50441342
Affinity DataIC50: 101nMpH: 7.5 T: 25°CAssay Description:Ten nanomolar of 6x Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Affinity DataIC50: >5.40E+4nMAssay Description:Inhibition of His-tagged XIAP BIR3 domain (241 to 356) (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.40E+4nMAssay Description:Inhibition of XIAP-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Inhibition of XIAP-BIR2 domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Inhibition of His-tagged XIAP BIR2 domain (124 to 240) (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair