BDBM50442144 CHEMBL2441272

SMILES O[C@H]1CC[C@@H](CC1)Nc1nc(Cc2ccccc2)cc(Nc2nc3ccc(cc3s2)C(F)(F)F)n1

InChI Key InChIKey=RWUJEVMUBYCUBS-UAPYVXQJSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442144   

TargetTyrosine-protein kinase ITK/TSK(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50442144(CHEMBL2441272)Copy SMILESCopy InChI

Affinity DataKi:  13nMAssay Description:Inhibition of recombinant human FLAG-tagged ITK using biotinylated GST-SAM68 as substrate after 30 minsMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50442144(CHEMBL2441272)Copy SMILESCopy InChI

Affinity DataKi:  251nMAssay Description:Inhibition of Aurora-B (unknown origin) using 5FAM-PKAtide as substrate after 120 minsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL