BDBM50442177 CHEMBL2441599::US9187424, 9

SMILES CCn1nnc(n1)C1=C(CC(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(C)cc1

InChI Key InChIKey=YTDRWNDMSGPTFZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50442177   

LigandPNGBDBM50442177(CHEMBL2441599 | US9187424, 9)
Affinity DataIC50: 121nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details
US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50442177(CHEMBL2441599 | US9187424, 9)
Affinity DataIC50: 121nMAssay Description:Inhibition of human MGAT2 by LC/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50442177(CHEMBL2441599 | US9187424, 9)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human MGAT2 by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50442177(CHEMBL2441599 | US9187424, 9)
Affinity DataIC50: 3.33E+4nMpH: 7.4 T: 2°CAssay Description:MGAT2 enzyme was assayed using membranes isolated from Sf9 cells expressing the recombinant human MGAT2 cDNA with 2-monooleoylglycerol and [3H]-oleoy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details
US Patent