BDBM50442259 CHEMBL2442124

SMILES C[C@@H](Sc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=FERXSPCVEYOEDT-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50442259   

TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50442259(CHEMBL2442124)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50442259(CHEMBL2442124)
Affinity DataIC50: 16nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50442259(CHEMBL2442124)
Affinity DataIC50: 336nMAssay Description:Inhibition of RON (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50442259(CHEMBL2442124)
Affinity DataIC50: 349nMAssay Description:Inhibition of ALK (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50442259(CHEMBL2442124)
Affinity DataIC50: 447nMAssay Description:Inhibition of AXL (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50442259(CHEMBL2442124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50442259(CHEMBL2442124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50442259(CHEMBL2442124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50442259(CHEMBL2442124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Abl (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50442259(CHEMBL2442124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TYRO3 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed