BDBM50442293 CHEMBL2442248

SMILES Cc1ccnc(NC(c2ccc(F)cc2)c2cc(Cl)c3cccnc3c2O)c1

InChI Key InChIKey=FRRVRVNGAKHMGO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442293   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Eutropics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50442293(CHEMBL2442248)
Affinity DataIC50: 500nMAssay Description:Inhibition of human GST-tagged Mcl1 expressed in Escherichia coli BL21 using FITC-AHA-MRPEIWIAQELRRIGDEFNA-[NH2] after 20 mins by fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed