BDBM50442296 CHEMBL2442245

SMILES Oc1c(cc(Cl)c2cccnc12)C(Nc1ccccn1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=HTXHEDGTGSQXTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442296   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Eutropics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50442296(CHEMBL2442245)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human GST-tagged Mcl1 expressed in Escherichia coli BL21 using FITC-AHA-MRPEIWIAQELRRIGDEFNA-[NH2] after 20 mins by fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed