BDBM50442353 CHEMBL2442888

SMILES CC(C)OC(=O)Nc1ccc(Oc2ccc(cc2)S(=O)(=O)CC2CS2)cc1

InChI Key InChIKey=FNTWGXGOCVTLKR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50442353   

Target72 kDa type IV collagenase(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442353(CHEMBL2442888)
Affinity DataKi:  680nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442353(CHEMBL2442888)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human recombinant MMP-14 catalytic domain using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50442353(CHEMBL2442888)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human recombinant MMP-9 catalytic domain using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed