BDBM50442649 CHEMBL2441929

SMILES COc1ccc(NC(=O)[C@@H]2C[C@H](C)CC[C@H]2C(C)C)cc1

InChI Key InChIKey=HNSGVPAAXJJOPQ-XOKHGSTOSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442649   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL

LigandBDBM50442649(CHEMBL2441929)Copy SMILESCopy InChI

Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at TRPM8 (unknown origin) by fluorometric imaging plate reader analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In DepthDetails PubMed
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TargetTransient receptor potential cation channel subfamily M member 8(Human)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL

LigandBDBM50442649(CHEMBL2441929)Copy SMILESCopy InChI

Affinity DataEC50:  40nMAssay Description:Inhibition of human TRPM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of WS12-induced Ca2+ elevation by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL