BDBM50442783 CHEMBL2440442

SMILES O=c1nc2n(-c3ccc(Cl)c(Cl)c3)c3c(C(F)(F)F)cccc3cc-2c(=O)[nH]1

InChI Key InChIKey=GZQBRMWMHNFFII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442783   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Nottingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442783BDBM50442783(CHEMBL2440442)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of GST-tagged HDM2 (unknown origin) assessed as p53 ubiquitination by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed