BDBM50442905 CHEMBL1526240::Dihydrogambogic-acid

SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]C1([#6])[#8]-c2c(-[#6]\[#6]=[#6](\[#6])-[#6])c3-[#8]C45[#6]6-[#6]-[#6](-[#6]=[#6]4-[#6](=O)-c3c(-[#8])c2-[#6]=[#6]1)-[#6](-[#8])C5([#6]\[#6]=[#6](\[#6])-[#6](-[#8])=O)[#8]C6([#6])[#6]

InChI Key InChIKey=VZXLWEWYBUGLJA-XKZIYDEJSA-N

Data  2 KI  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50442905   

TargetSolute carrier organic anion transporter family member 1B1(Human)
Ku Leuven

Curated by ChEMBL

LigandBDBM50442905(CHEMBL1526240 | Dihydrogambogic-acid)Copy SMILESCopy InChI

Affinity DataKi:  1.23E+3nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetSolute carrier organic anion transporter family member 1B3(Human)
Ku Leuven

Curated by ChEMBL

LigandBDBM50442905(CHEMBL1526240 | Dihydrogambogic-acid)Copy SMILESCopy InChI

Affinity DataKi:  2.24E+3nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetSolute carrier organic anion transporter family member 1B3(Human)
Ku Leuven

Curated by ChEMBL

LigandBDBM50442905(CHEMBL1526240 | Dihydrogambogic-acid)Copy SMILESCopy InChI

Affinity DataIC50:  2.88E+3nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetReplicase polyprotein 1ab(2019-nCoV)
Institut Pasteur Korea

LigandBDBM50442905(CHEMBL1526240 | Dihydrogambogic-acid)Copy SMILESCopy InChI

Affinity DataIC50:  1.34E+4nMAssay Description:Ten-point DRCs were generated for each drug. Vero cells were seeded at 1.2 × 104 cells per well in DMEM, supplemented with 2% FBS and 1× ...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetSolute carrier organic anion transporter family member 1B1(Human)
Ku Leuven

Curated by ChEMBL

LigandBDBM50442905(CHEMBL1526240 | Dihydrogambogic-acid)Copy SMILESCopy InChI

Affinity DataIC50:  2.24E+3nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL