BDBM50443272 CHEMBL5283663

SMILES CN(C)c1cccc(Nc2ncc3c(n2)n(-c2cccc(n2)C(C)(C)O)n(CC=C)c3=O)c1

InChI Key InChIKey=NKRFOICHBBXLLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50443272   

TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50443272(CHEMBL5283663 | US12220415, Compound KAC-019)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant Wee1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50443272(CHEMBL5283663 | US12220415, Compound KAC-019)
Affinity DataIC50: 6.30nMAssay Description:A LanthaScreen kinase activity assay was conducted to assess WEE1 kinase inhibitory activity for compounds of this disclosure. LanthaScreen Eu time-r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent