BDBM50443583 CHEMBL3091981

SMILES O=C1NCC2(C[C@@H]3CCCC[C@@H]3[C@H]2C=Cc2ccc(-c3cccc(F)c3)cn2)O1

InChI Key InChIKey=YFICELBHPPRCPC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443583   

TargetProteinase-activated receptor 1(Human)
Korea Research Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443583BDBM50443583(CHEMBL3091981)
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Korea Research Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443583BDBM50443583(CHEMBL3091981)
Affinity DataIC50: 8.60nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Korea Research Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443583BDBM50443583(CHEMBL3091981)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed