BDBM50443711 CHEMBL3093862::US9238658, 35

SMILES OCC(=O)N1CCc2nc(NC(=O)N3CCC(CC3)N3CCc4ccc(F)cc34)sc2C1

InChI Key InChIKey=ZZKPGGXACUXCPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50443711   

TargetAcyl-CoA desaturase 1(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443711(CHEMBL3093862 | US9238658, 35)
Affinity DataIC50: 96nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetAcyl-CoA desaturase 1(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443711(CHEMBL3093862 | US9238658, 35)
Affinity DataIC50: 96nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using Stearoyl-[9,10-3H]-CoA as substrate assessed as [3H2O] generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed