BDBM50443713 CHEMBL3093860::US9238658, 36

SMILES Fc1ccc2CCN(C3CCN(CC3)C(=O)Nc3nc4CCNCc4s3)c2c1

InChI Key InChIKey=PXOQMUPPNGWVGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50443713   

TargetAcyl-CoA desaturase 1(Rat)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50443713(CHEMBL3093860 | US9238658, 36)
Affinity DataIC50: 29nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using Stearoyl-[9,10-3H]-CoA as substrate assessed as [3H2O] generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50443713(CHEMBL3093860 | US9238658, 36)
Affinity DataIC50: 29nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent