BDBM50443723 CHEMBL3093867::US9238658, 13

SMILES Cc1csc(NC(=O)N2CCC(CC2)N2CCCc3ccccc23)n1

InChI Key InChIKey=YSVPSHBMLVQCFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50443723   

TargetAcyl-CoA desaturase 1(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443723(CHEMBL3093867 | US9238658, 13)
Affinity DataIC50: 491nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent

TargetAcyl-CoA desaturase 1(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443723(CHEMBL3093867 | US9238658, 13)
Affinity DataIC50: 491nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using Stearoyl-[9,10-3H]-CoA as substrate assessed as [3H2O] generationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed